Susceptibility to Gold Nanoparticle-Induced Hepatotoxicity is Enhanced in a Mouse Model of Nonalcoholic Steatohepatitis

Publication year: 2012 Source: Toxicology, Available online 28 January 2012 Jung Hwan Hwang, Soo Jin Kim, Yong-Hoon Kim, Jung-Ran Noh, Gil-Tae Gang, … Although the safety of gold nanoparticle (AuNP) use is of growing concern, most toxicity studies of AuNPs had focused on their chemical characteristics, including their physical dimensions, surface chemistry, and shape. The present study examined the susceptibility of rodents with healthy or damaged livers to AuNP-induced hepatotoxicity.

Publication year: 2012 Source: Toxicology, Available online 28 January 2012 Jung Hwan Hwang, Soo Jin Kim, Yong-Hoon Kim, Jung-Ran Noh, Gil-Tae Gang, … Although the safety of gold nanoparticle (AuNP) use is of growing concern, most toxicity studies of AuNPs had focused on their chemical characteristics, including their physical dimensions, surface chemistry, and shape. The present study examined the susceptibility of rodents with healthy or damaged livers to AuNP-induced hepatotoxicity.

Taken from:
Susceptibility to Gold Nanoparticle-Induced Hepatotoxicity is Enhanced in a Mouse Model of Nonalcoholic Steatohepatitis