Waltham, MA-based Radius Health’s investigational drug abaloparatide-SC (subcutaneous) increases bone mineral density in the spine and hip in postmenopausal women with osteoporosis and may reduce their risk of vertebral and nonvertebral fractures, according to research presented April 1 at Endo 2016, the annual meeting of the Endocrine Society, in Boston. Researchers investigated patients enrolled in the randomized, double-blind, comparative, multicenter international phase 3 ACTIVE clinical trial to evaluate the efficacy and safety of 80 µg of abaloparatide-SC for preventing fractures in otherwise healthy ambulatory postmenopausal women with osteoporosis. Overall, 2463 patients aged between 49 and 86 years were randomized to one of three treatment arms for 18 months: double-blind 80 µg of abaloparatide-SC, blind-matched placebo, or open-label 20 µg of subcutaneous teriparatide
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Radius Health drug cuts fracture risk