The complex landscape of genetic alterations in mantle cell lymphoma

Publication year: 2011 Source: Seminars in Cancer Biology, Available online 17 September 2011 Cristina Royo, Itziar Salaverria, Elena M. Hartmann, Andreas Rosenwald, Elías Campo, … Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) which deregulates cyclin D1. Small subsets of cases have been identified with variantCCND1translocations with the immunoglobulin light chain genes or with alternative translocations involvingCCND2andCCND3.

Publication year: 2011 Source: Seminars in Cancer Biology, Available online 17 September 2011 Cristina Royo, Itziar Salaverria, Elena M. Hartmann, Andreas Rosenwald, Elías Campo, … Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) which deregulates cyclin D1. Small subsets of cases have been identified with variantCCND1translocations with the immunoglobulin light chain genes or with alternative translocations involvingCCND2andCCND3.

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The complex landscape of genetic alterations in mantle cell lymphoma

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