Publication year: 2011 Source: Seminars in Cancer Biology, Available online 1 October 2011 Raya Saab Cellular senescence is a tumor suppressor response that has been observed both in vitro and in vivo, and features of senescence have been documented in various human premalignant lesions, including melanoma, colon and lung adenoma, prostatic intraepithelial neoplasia, and others.
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Senescence and pre-malignancy: how do tumors progress?