Publication year: 2011 Source: Seminars in Cancer Biology, Available online 15 October 2011 Jerry W. Shay, Woodring E. Wright There is mounting evidence for the existence of an important relationship between telomeres and telomerase and cellular aging and cancer. Normal human cells progressively lose telomeres with each cell division until a few short telomeres become uncapped leading to a growth arrest known as replicative aging.
Role of Telomeres and Telomerase in Cancer
Publication year: 2011 Source: Seminars in Cancer Biology, Available online 15 October 2011 Jerry W. Shay, Woodring E. Wright There is mounting evidence for the existence of an important relationship between telomeres and telomerase and cellular aging and cancer. Normal human cells progressively lose telomeres with each cell division until a few short telomeres become uncapped leading to a growth arrest known as replicative aging.