Ribonucleotide reductase inhibition by p-alkoxyphenols studied by molecular docking and molecular dynamics simulations

Publication year: 2011 Source: Archives of Biochemistry and Biophysics, Available online 17 September 2011 Jinghui Luo, Astrid Gräslund Ribonucleotide reductase (RNR) is necessary for production of the precursor deoxyribonucleotides for DNA synthesis. Class Ia RNR functions via a stable free radical in one of the two components protein R2.

Publication year: 2011 Source: Archives of Biochemistry and Biophysics, Available online 17 September 2011 Jinghui Luo, Astrid Gräslund Ribonucleotide reductase (RNR) is necessary for production of the precursor deoxyribonucleotides for DNA synthesis. Class Ia RNR functions via a stable free radical in one of the two components protein R2.

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Ribonucleotide reductase inhibition by p-alkoxyphenols studied by molecular docking and molecular dynamics simulations