Recombinant human platelet-derived growth factor-BB versus autologous bone graft in foot and ankle fusion: A systematic review and meta-analysis

Publication date: Available online 17 February 2016 Source: Foot and Ankle Surgery Author(s): Han Sun, Pei-Pei Lu, Ping-Hui Zhou, Si-Wei Sun, Hong-Tao Zhang, Yi-Jie Liu, Xu Yang, Xiao-Feng Shen, Hui-Lin Yang Today, autogenous bone graft (ABG) is still considered as the gold standard for joint fusion. Recombinant human platelet-derived growth factor-BB (rhPDGF-BB) which is of chemotactic and mitogenic to mesenchymal stem cells and possesses outstanding osteogenetic potentials has been used for ankle and foot fusion in recent years.

Publication date: Available online 17 February 2016 Source: Foot and Ankle Surgery Author(s): Han Sun, Pei-Pei Lu, Ping-Hui Zhou, Si-Wei Sun, Hong-Tao Zhang, Yi-Jie Liu, Xu Yang, Xiao-Feng Shen, Hui-Lin Yang Today, autogenous bone graft (ABG) is still considered as the gold standard for joint fusion. Recombinant human platelet-derived growth factor-BB (rhPDGF-BB) which is of chemotactic and mitogenic to mesenchymal stem cells and possesses outstanding osteogenetic potentials has been used for ankle and foot fusion in recent years.

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Recombinant human platelet-derived growth factor-BB versus autologous bone graft in foot and ankle fusion: A systematic review and meta-analysis