Promising target to protect bone in patients with diabetes

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes. In a study published in Nature Communications , the investigators report that hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes. In a study published in Nature Communications , the investigators report that hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.

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Promising target to protect bone in patients with diabetes