Publication year: 2011 Source: Seminars in Cancer Biology, Available online 20 July 2011 Ingrid Øra, Angelika Eggert Close international collaboration between pediatric oncologists has led to marked improvements in the cure of patients, seen as a long-term overall survival rate of about 80%. Despite this progress, neuroblastoma remains a challenging disease for both clinicians and researchers. Major clinical problems include lack of acceptable cure rates in high-risk neuroblastoma and potential overtreatment of subsets of patients at low and intermediate risk of the disease.
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Progress in treatment and risk stratification of neuroblastoma: Impact on future clinical and basic research