Posttranslational regulation of AMPA receptor trafficking and function

Publication year: 2011 Source: Current Opinion in Neurobiology, Available online 14 October 2011 Wei Lu, Katherine W Roche In the mammalian central nervous system, the majority of fast excitatory synaptic transmission is mediated by glutamate acting on AMPA-type ionotropic glutamate receptors. The abundance of AMPA receptors at the synapse can be modulated through receptor trafficking, which dynamically regulates many fundamental brain functions, including learning and memory

Publication year: 2011 Source: Current Opinion in Neurobiology, Available online 14 October 2011 Wei Lu, Katherine W Roche In the mammalian central nervous system, the majority of fast excitatory synaptic transmission is mediated by glutamate acting on AMPA-type ionotropic glutamate receptors. The abundance of AMPA receptors at the synapse can be modulated through receptor trafficking, which dynamically regulates many fundamental brain functions, including learning and memory

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Posttranslational regulation of AMPA receptor trafficking and function

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