Nano-sized calcium phosphate (CaP) carriers for non-viral gene deilvery

Publication year: 2011 Source: Materials Science and Engineering: B, Available online 12 November 2011 Donghyun Lee, Kalpesh Upadhye, Prashant N. Kumta Gene therapy has garnered much interest due to the potential for curing multiple inherited and/or acquired diseases increases. As a result, there has been intense activity from multiple research groups for developing effective delivery methods and carriers, a critical step in advancing gene delivery technologies. In order for the carriers to effectively deliver the payloads, multiple extracellular and intracellular barriers need to be overcome.

Publication year: 2011 Source: Materials Science and Engineering: B, Available online 12 November 2011 Donghyun Lee, Kalpesh Upadhye, Prashant N. Kumta Gene therapy has garnered much interest due to the potential for curing multiple inherited and/or acquired diseases increases. As a result, there has been intense activity from multiple research groups for developing effective delivery methods and carriers, a critical step in advancing gene delivery technologies. In order for the carriers to effectively deliver the payloads, multiple extracellular and intracellular barriers need to be overcome.

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Nano-sized calcium phosphate (CaP) carriers for non-viral gene deilvery