Publication year: 2011 Source: European Psychiatry, Available online 20 September 2011 P. Fusar-Poli, P. McGuire, S. Borgwardt The onset of schizophrenia is usually preceded by a prodromal phase characterized by functional decline and subtle prodromal symptoms, which include attenuated psychotic phenomena, cognitive deterioration and a decline in socio-occupational function. Preventive interventions during this phase are of great interest because of the impressive clinical benefits. However, available psychopathological criteria employed to define a high risk state for psychosis have low validity and specificity.
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Mapping prodromal psychosis: A critical review of neuroimaging studies