Publication year: 2011 Source: Experimental Parasitology, Available online 12 October 2011 Tania C. Felizardo, Maria I. Elsas, Gloria M.C.A. Lima, Ises A. Abrahamsohn Lesion development in tegumentary leishmaniasis is markedly influenced by the inoculation site and the type and number of injected infective forms. This and the yet unclear contribution of Th2 cytokines as susceptibility factors toL. amazonensisinfection prompted us to investigate the roles of IL-4, IL-13 and IL-10 on C57BL/6 and BALB/c mice infected in the footpad (paw) or rump with low-doseL
Lack of signaling by IL-4 or by IL-4/IL-13 has more attenuating effects onL. amazonensisdorsal skin- than on footpad-infected mice
Publication year: 2011 Source: Experimental Parasitology, Available online 12 October 2011 Tania C. Felizardo, Maria I. Elsas, Gloria M.C.A. Lima, Ises A. Abrahamsohn Lesion development in tegumentary leishmaniasis is markedly influenced by the inoculation site and the type and number of injected infective forms. This and the yet unclear contribution of Th2 cytokines as susceptibility factors toL. amazonensisinfection prompted us to investigate the roles of IL-4, IL-13 and IL-10 on C57BL/6 and BALB/c mice infected in the footpad (paw) or rump with low-doseL