Publication year: 2011 Source: Tissue and Cell, Available online 6 September 2011 Jinlong Huang, Shukui Wang, Cui Wei, Yan Xu, Ying Wang, … A hybrid hydrogel (PP) composed of Polomaxer-407 (PO) and octapeptide with amino acid sequence of KFEFKFEF (PE) was prepared to make a scaffold material incorporating PO’s high and tunable mechanical strength and integrity with PE’s superior bioactivity. Human adipose-derived mesenchymal stem cells (hASCs) were encapsulated into PE, PO and PP hydrogels respectively and injected subcutaneously at the dorsal neck area of nude mice
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In vivodifferentiation of adipose-derived stem cells in an injectable poloxamer-octapeptide hybrid hydrogel