Publication year: 2011 Source: Journal of Cardiac Failure, Available online 3 September 2011 Gaia Cattadori, Jean-Paul Schmid, Nicolas Brugger, Erica Gondoni, Pietro Palermo, … BackgroundExercise performance improvement after training in heart failure (HF) can be due to central or peripheral changes.Methods and ResultsIn 70 HF stable patients we measured peak VO2and cardiac output (CO, inert gas rebreathing technique) and calculated arteriovenous O2differences (a-v O2diff) before and after an 8-week training program. Peak VO2changed from 1111 ± 403 mL/minute to 1191 ± 441 (P< .001), peak workload from 68 ± 29 watts to 76 ± 32 (P< .0001), peakCO from 6.6 ± 2.2 L/minute to 7.3 ± 2.5 (P< .0001), and peak a-v O2diff from 17.5 ± 5.1 mL/100 mL to 16.6 ± 4.1 (P = .081).
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Hemodynamic Effects of Exercise Training in Heart Failure