Dysfunctional wound healing in diabetic foot ulcers: New crossroads

Diabetic foot ulcerations affect 25 percent of patients with diabetes mellitus during their lifetime and constitute a major health problem as they are often recalcitrant to healing due to a constellation of both intrinsic and extrinsic factors. The purpose of this review is to (1) detail the current mechanistic understanding of DFU formation and (2) highlight future therapeutic targets.

Diabetic foot ulcerations affect 25 percent of patients with diabetes mellitus during their lifetime and constitute a major health problem as they are often recalcitrant to healing due to a constellation of both intrinsic and extrinsic factors. The purpose of this review is to (1) detail the current mechanistic understanding of DFU formation and (2) highlight future therapeutic targets.

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Dysfunctional wound healing in diabetic foot ulcers: New crossroads