Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1

Publication year: 2011 Source: Cellular Signalling, Available online 1 October 2011 Klaus Deckmann, Florian Rörsch, Gerd Geisslinger, Sabine Grösch Dimethylcelecoxib, a non COX-2 inhibiting derivative of celecoxib, inhibits PGE2synthesis by transcriptional inhibition of mPGES-1.

Publication year: 2011 Source: Cellular Signalling, Available online 1 October 2011 Klaus Deckmann, Florian Rörsch, Gerd Geisslinger, Sabine Grösch Dimethylcelecoxib, a non COX-2 inhibiting derivative of celecoxib, inhibits PGE2synthesis by transcriptional inhibition of mPGES-1.

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Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1

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