Changes in prescription patterns before and after reporting of ENHANCE results and expected effects on LDL-C reduction

Publication year: 2011 Source: Journal of Clinical Lipidology, Available online 7 December 2011 Peter P Toth, Christie M. Ballantyne, Michael H. Davidson, Joanne E. Tomassini, Dena Rosen Ramey, … BackgroundRecent trends suggest decreased utilization of ezetimibe/simvastatin combination and coadministered ezetimibe+statin therapies.ObjectiveThis analysis evaluated changes in prescription patterns for ezetimibe/simvastatin, ezetimibe+statins and statin therapies and expected effects on LDL-C lowering during 2007-2008.MethodsPrescription pattern changes were assessed using patient-level data from the IMS Health Longitudinal Rx database during two time periods, July 14, 2007-January 13, 2008 (n=8,813,674) and January 14, 2008-July 13, 2008 (n=9,131,030), 6-months before and after reporting of the results of The Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) trial on January 14, 2008

Publication year: 2011 Source: Journal of Clinical Lipidology, Available online 7 December 2011 Peter P Toth, Christie M. Ballantyne, Michael H. Davidson, Joanne E. Tomassini, Dena Rosen Ramey, … BackgroundRecent trends suggest decreased utilization of ezetimibe/simvastatin combination and coadministered ezetimibe+statin therapies.ObjectiveThis analysis evaluated changes in prescription patterns for ezetimibe/simvastatin, ezetimibe+statins and statin therapies and expected effects on LDL-C lowering during 2007-2008.MethodsPrescription pattern changes were assessed using patient-level data from the IMS Health Longitudinal Rx database during two time periods, July 14, 2007-January 13, 2008 (n=8,813,674) and January 14, 2008-July 13, 2008 (n=9,131,030), 6-months before and after reporting of the results of The Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) trial on January 14, 2008

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Changes in prescription patterns before and after reporting of ENHANCE results and expected effects on LDL-C reduction