Beneficial clinical effects but limited tissue quality following osteochondral repair with a cell-free multilayered nano-composite scaffold in the…

Publication date: Available online 5 October 2016 Source: Foot and Ankle Surgery Author(s): Martin Kaipel, Markus Schreiner, Richard Kellner, Joachim Klikovits, Sebastian Apprich, Martin Brix, Harald Boszotta, Stephan Domayer, Siegfried Trattnig Background The treatment of larger osteochondral lesions of the talus remains an operative challenge. In addition to micro fracturing and osteochondral transplantation one promising strategy could be the operative repair with a cell-free multilayered nano-composite scaffold with the potential to regenerate bone and cartilage in one treatment. Methods In this prospective case series four consecutive patients who suffered from a single osteochondral lesion (≥1.5 cm2) on the medial talus were enrolled.

Publication date: Available online 5 October 2016 Source: Foot and Ankle Surgery Author(s): Martin Kaipel, Markus Schreiner, Richard Kellner, Joachim Klikovits, Sebastian Apprich, Martin Brix, Harald Boszotta, Stephan Domayer, Siegfried Trattnig Background The treatment of larger osteochondral lesions of the talus remains an operative challenge. In addition to micro fracturing and osteochondral transplantation one promising strategy could be the operative repair with a cell-free multilayered nano-composite scaffold with the potential to regenerate bone and cartilage in one treatment. Methods In this prospective case series four consecutive patients who suffered from a single osteochondral lesion (≥1.5 cm2) on the medial talus were enrolled.

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Beneficial clinical effects but limited tissue quality following osteochondral repair with a cell-free multilayered nano-composite scaffold in the…