Publication year: 2011 Source: Seminars in Cancer Biology, Available online 16 September 2011 Matthew Hoare, Andrew RJ Young, Masashi Narita Autophagy, one of two major intracellular degradation pathways, plays a critical role in energy homeostasis and the quality control of macromolecules and intracellular organelles. Previous work has demonstrated the importance of autophagy in maintaining cellular fitness, both in healthy and stressful conditions, revealing the complex interplay between autophagy and other stress-responsive phenotypes
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Autophagy in cancer: having your cake and eating it.