Publication year: 2011 Source: Cellular Signalling, Available online 21 September 2011 Simona Weisheit, Claus Liebmann Recently, we described a novel function of over-expressed protein kinase Cε (PKCε) as a negative allosteric modulator of EGFR signalling in several head and neck squamous carcinoma (HNSCC) cell lines.
Allosteric modulation by protein kinase Cε leads to modified responses of EGF receptor towards tyrosine kinase inhibitors
Publication year: 2011 Source: Cellular Signalling, Available online 21 September 2011 Simona Weisheit, Claus Liebmann Recently, we described a novel function of over-expressed protein kinase Cε (PKCε) as a negative allosteric modulator of EGFR signalling in several head and neck squamous carcinoma (HNSCC) cell lines.